Neuroanatomical correlates of psychosis in temporal lobe epilepsy: voxel-based morphometry study
نویسندگان
چکیده
منابع مشابه
Neuroanatomical correlates of psychosis in temporal lobe epilepsy: voxel-based morphometry study.
BACKGROUND Temporal lobe epilepsy is associated with a significant risk of psychosis but there are only limited studies investigating the underlying neurobiology. AIMS To characterise neuroanatomical changes in temporal lobe epilepsy and comorbid psychosis. METHOD The study population comprised all individuals with temporal lobe epilepsy on the epilepsy database at the National Centre for E...
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Background Partial epilepsy represents almost 70% of the epileptic syndrome. It is characterized by partial seizures that arise from the restricted area of the cerebral cortex. Temporal lobe epilepsy (TLE) is the most frequent form of cryptogenic partial epilepsies [1]. The mesial temporal sclerosis is the pathologic abnormality most frequently detected in post mortem studies of subjects with T...
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BACKGROUND Conventional volumetric studies have shown that brain structures functionally and anatomically related to the hippocampus are smaller in patients with drug-refractory medial temporal lobe epilepsy (MTLE). OBJECTIVES To determine the extent of gray matter atrophy in the brains of patients with MTLE and to examine the pattern of atrophy. DESIGN We performed a voxel-based morphometr...
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ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 2010
ISSN: 0007-1250,1472-1465
DOI: 10.1192/bjp.bp.110.080218